blog bug: What

Showing posts with label What. Show all posts

Thursday, August 15, 2013

From Harmless Colonizers to Virulent Pathogens: Microbiologists Identify What Triggers Disease.

The bacteria Streptococcus pneumoniae harmlessly colonizes the mucous linings of throats and noses in most people, only becoming virulent when they leave those comfortable surroundings and enter the middle ears, lungs or bloodstream. Now, in research published in July in mBio, University at Buffalo researchers reveal how that hapPENS.what is the mechanism behind what makes us sick?" explains Anders P. Hakansson, PhD, assistant professor of microbiology and immunology in the UB School of Medicine and Biomedical Sciences. "We are looking to find ways to interfere with the transition to disease. Few have looked at the specific mechanism that suddenly makes these bacteria leave the nose where they typically prefer to reside and travel into the lungs or the middle ear where they cause disease. If we can understand that process, then maybe we can block it."Hakansson and his colleagues had previously found that when the pneumococci colonize the nose, they form sophisticated, highly structured biofilm communities.In the current study, the research team grew biofilms of pneumococci on top of human epithelial cells, where the bacteria normally grow. They then infected these bacteria with influenza A virus or exposed them to the conditions that typically accompany the flu, including increased temperature to mimic fever, increased concentrations of ATP (the energy molecule in cells), and the stress hormone norepinephrine, released during flu infection. All three stimuli triggered a sudden release and departure of bacteria from the biofilm in the nose into otherwise normally sterile organs, such as the middle ears and lungs or into the bloodstream. At the same time, the researchers found that the gene expression profile of the bacteria that had dispersed from the biofilms revealed far more virulence.Hakansson says the research demonstrates how the mammalian and bacterial kingdoms interact. "Humans are the only natural hosts for these bacteria," he explains, "when the viral infection comes in, there is this interkingdom signaling, where the bacteria respond to host molecules. If we can find ways to interrupt that signaling, we might be able to prevent disease."

Hakansson is affiliated with the Witebsky Center for Microbial Pathogenesis and Immunology and the New York State Center of Excellence in Bioinformatics and Life Sciences, both at UB. The major portion of the work was conducted by co-author Laura R. Marks, an MD/PhD candidate in the UB Department of Microbiology and Immunology, with co-authors Bruce A. Davidson, research assistant professor of anesthesiology and Paul R. Knight, III, MD, PhD, professor of anesthesiology and microbiology and immunology.The work was funded by the UB Department of Microbiology and Immunology.
Source:http://microbiologycenter.blogspot.com/2013/08/from-harmless-colonizers-to-virulent.html

From Harmless Colonizers to Virulent Pathogens: Microbiologists Identify What Triggers Disease. Images

harmless colonizers to virulent pathogens: UB microbiologists identify ...
(447 x 297 - 56.27 KB - jpeg)

Bacteria Sent To ISS Survive For 500+ Days - Space News - redOrbit
(1600 x 1200 - 599.81 KB - jpeg)

... disease mosquito borne disease virus west nile virus mosquito mosquito
(1000 x 675 - 589.40 KB - jpeg)

Infection Prevention for Outpatient Care - Page 3
(598 x 449 - 53.94 KB - jpeg)

Monday, August 12, 2013

What it takes to make it as a modern female pop star

"At first glance, I didn't realize the most notable thing about the video, as I was totally distracted by McKee's very bright candy-colored hair: it's that she actually wrote every song she was performing. "Hold It Against Me." "Teenage Dream." "Dynamite." "Last Friday Night (T.G.I.F)." "Part Of Me." "C'Mon." "California Girls." "Wide Awake."" - Jezebel
Source:http://girlsmediamystery.blogspot.com/2013/07/what-it-takes-to-make-it-as-modern.html

What it takes to make it as a modern female pop star Images

Bonnie McKee and What It Takes to Make a Modern Female Pop Star
(320 x 436 - 89.21 KB - jpeg)

Bonnie McKee and What It Takes to Make a Modern Female Pop Star
(320 x 180 - 45.87 KB - jpeg)

Katy Perry Reinvents Herself By Setting Fire To Her Blue Wig
(640 x 360 - 128.36 KB - jpeg)

Bonnie McKee Talks Songwriting Success, Industry Politics & Second ...
(936 x 1407 - 884.80 KB - jpeg)

Thursday, May 9, 2013

What About The Victims?

It's been almost two weeks since the bombing in Boston.The victims' are slowly coming to grips with their injuries and the tragic losses they must learn to deal with.Could someone please explain to me why, after nearly fourteen days , we are still seeing "their" (terrorists), faces all over the news? I don't care what "they" look like. I'm quite sure Boston residents' don't want to see "them" everyday.Boston lost so much that day, but with the losses they have managed to come out even stronger.

The finish line of the Boston Marathon as 1st bomb detonatedHow about we give the victims' some air time? Let's focus on their healing.I am very disturbed at how television and other forms of media make "them" (terrorists), the centre of attention. Almost to the point of celebrity status.

Krystle Campbell described as ambitious and loving.For instance, eight year old Martin Richard, I wonder how Martin's family feel about seeing their little boy's murderer on T.V. day after day? Or how about Lingzi Lu's family? Sean Collier's? Krystle Campbell's? When do the victims and their families get some rights?

Sean Collier MIT Officer shot and killed 4 days after bombing.

Martin Richard 8 years oldGoing as far back as the 1995 Oklahoma City bombing - I wouldn't be able to tell you who the victims' were - BUT - I would know Timothy McVeigh's face. He was another terrorist who got more coverage than he deserved.

Lingzi Lu Boston U. Grad studentSame thing goes for the terrorists' families. The majority of the people, I think, would concur - we don't care how they feel.Stop making these terrible, heinous terrorists the focus. They lost that right when they decided to turn Boston and the surrounding area into a war zone.You caught him - let's forget him.If you would like to help with the victims' costs of recovery please go to www.gofundme.com . They will need all the help they can get.just my point of view... :o)
Source:http://ahousewifespointofview.blogspot.com/2013/04/what-about-victims.html

What About The Victims? Images